Home REVIEWS Top 10 Best Sleep Supplements: Highest Potency

Top 10 Best Sleep Supplements: Highest Potency

by Julia Higgins

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myPEAK DeltaSleep is our pick for best natural sleep supplement, with Nested Naturals Luna, Relaxium Sleep, and SugarBear Sleep Aid Gummies coming in close behind. Read on for the full list, plus tips for choosing the best sleep supplements for you.

A quick look at the best sleep supplements

If you struggle with poor sleep quality, selecting the right sleep aid is crucial for achieving rest that’s both rejuvenating and restorative. These days, a plethora of sleep supplements flood the market, ranging from more herbal remedies like melatonin and passionflower tea to those that are chock-full of natural active ingredients subject to rigorous research. We’ve rounded up ten of the best sleep supplements available in the hopes of pointing those grappling with sleep issues in the right direction.

While some are blessed with the ability to drift off the moment they get into bed, if you struggle with poor sleep quality, fret not—there are workarounds. Sleep aids have been around for centuries in one form or another, and modern science has made carefully developed sleep supplements readily available, offering a wealth of options both behind the counter and on the shelf.

In choosing the best sleep supplements, we explored each product’s ingredients, looking only for those that would qualify as a non habit forming sleep aid. We also considered the targeted health benefits of each product, ease of consumption, pricing, and how much research exists on at least one active ingredient in each supplement.

As a reminder, not all sleep supplements available over-the-counter are evaluated or approved by the FDA. They cannot claim to diagnose, prevent, treat, or cure issues associated with poor sleep. These products may serve as adjuncts to conventional therapies prescribed by and administered under the care of a licensed healthcare professional.

Top 10 best sleep supplements is an original (HealthXwire) article.

HealthXWire's picks of the best sleep supplements

The overall best sleep supplement

4.9 (68+) FROM myPEAKSUPPLEMENTS

mypeak delta sleep
  • Special Ingredients: Chamomile extract, GABA, niacin, natural melatonin, valerian root powder, Nu-FLOW® and Nu-Mag®
  • Sourcing: Physician formulated, lab tested, cGMP certified, and manufactured in the USA with clinically proven ingredients in an FDA registered facility
  • Targeted Benefits: Designed to help you fall asleep faster, cycle through deep sleep stages, relax muscles, reduce stress, and wake up feeling refreshed
  • Cost: Moderately priced ($$)
  • Customer Rating: 4.9 out of 5.0 stars
  • Our Expert Rating: 4.9 out of 5.0 stars

*Price is accurate as of the date of publication.

The Review

1. Ingredients: myPEAK DeltaSleep contains seven active ingredients. The star lineup includes chamomile extract, vitamin B3 (also known as niacin), gamma-aminobutyric acid (GABA), valerian root powder, passionflower extract, low levels of natural melatonin, and Nu-Flow® and Nu-Mag®, which are clean,  natural alternatives to toxic agents magnesium stearate and stearic acid.

2. Targeted Benefits: myPEAK DeltaSleep is designed to help you fall asleep faster, cycle through deep sleep stages, relax muscles, reduce stress, and wake up feeling refreshed.

3. Medical Research: Part of what makes myPEAK DeltaSleep one of the best sleep supplements is its physician-formulated makeup; all of its ingredients are backed by scientific studies.

4. Method of Consumption: myPEAK DeltaSleep is simple to take: Take one capsule with water 30 minutes before bedtime. The capsules are small, meaning that even the pill-adverse may find a friend in these.

5. Price: A single bottle comes with 30 supplements (a month’s supply) and will set you back around $30. Shipping is free, and if you find that myPEAK DeltaSleep works for you, you can choose to subscribe and save—monthly shipments will cost just over $24. Those with HSA or FSA plans can also use those to purchase this non habit forming sleep aid.

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About myPEAK DeltaSleep

myPEAK DeltaSleep is a deep sleep supplement that contains only natural ingredients. “DeltaSleep is physician-formulated and science-based with carefully selected ingredients for optimizing your deep sleep cycles, reducing stress and inducing calm, and helping ease you into a rejuvenating night of sleep,” says myPEAK co-founder, CEO, and Chief Scientific Officer Dr. Barghav Patel.

Positives
  • The formula is rife with science-backed ingredients that have been shown to promote sleep.
  • It’s a contender for the best GABA supplement for sleep.
Concerns
  • The price may be a little high for some.

Best stress-relieving sleep aid

4.3 (7.7K+) FROM AMAZON

LES Labs Cortisol Health
  • Special Ingredients: Magnesium citrate, ashwagandha root extract, phosphatidylserine, magnolia bark extract, and rhodiola root extract
  • Sourcing: Manufactured in the USA, plant-based, gluten-free, non-GMO
  • Targeted Benefits: Balancing cortisol response to induce relaxation and promote sleep
  • Cost: Moderately priced ($$)
  • Customer Rating: 4.3 out of 5.0 stars
  • Our Expert Rating: 4.4 out of 5.0 stars

*Price is accurate as of the date of publication.

The Review

1. Ingredients: Within each LES Labs Cortisol Health capsule are magnesium citrate, ashwagandha root extract, phosphatidylserine, magnolia bark extract, and rhodiola root extract.

2. Targeted Benefits: In the wide world of sleep supplements, this one is focused most specifically on balancing your cortisol response, aiming to induce relaxation and promote sleep.

3. Medical Research: Phosphatidylserine is a phospholipid that’s been studied for its capacity to control cortisol levels triggered by acute stress. Similarly, there is a great deal of research on magnesium, an essential mineral known for diminishing stress responses.

4. Method of Consumption: This non habit forming sleep aid comes in capsule form, and the recommended starting dosage is 1 capsule. During times of intense stress, the dose may be increased to 2 capsules.

5. Price: One bottle is priced at $33 and comes with 60 capsules; that provides a 1-2 month supply, depending on your ongoing stress levels. Buying in bulk will bring the price-per-bottle down, with a five-pack coming in at just $26.39 each.

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About LES Labs Cortisol Health

LES Labs Cortisol Health aims to help you find sleep by reducing cortisol levels, claiming that “this natural supplement is the daily key to unlocking a life of peace and calm.”

Positives
  • If your poor sleep quality is related to stress, this may be your best option.
Concerns
  • Reports of occasional stomach discomfort have arisen from consumers.
  • Since this supplement is so stress-oriented, those who aren’t experiencing elevated cortisol levels may not reap the benefits of it as fully.

Best herbal formula

3.8 (16.2K+) FROM AMAZON

  • Special Ingredients: Valerian root, lemon balm, passionflower, hops, and chamomile;GABA and L-Theanine; melatonin
  • Sourcing: Vegan, non-GMO, third-party lab tested, gluten-free
  • Targeted Benefits: Natural ingredients to help you fall asleep, stay asleep, and wake up refreshed
  • Cost: Moderately priced ($$)
  • Customer Rating: 8 out of 5.0 stars
  • Our Expert Rating: 0 out of 5.0 stars

*Price is accurate as of the date of publication.

The Review

1. Ingredients: Luna is formulated with a combination of melatonin, herbs, and amino acids. Among the included herbs are valerian root, lemon balm, passionflower, hops, and chamomile; the two key amino acids within the formula are GABA and L-Theanine.

2. Targeted Benefits: Luna is a deep sleep supplement that aims to capitalize on natural ingredients to help you fall asleep, stay asleep, and wake up in the morning without a hint of grogginess.

3. Medical Research: In addition to melatonin, which has been widely studied for its potential effects on sleep, Luna includes GABA and L-Theanine, two amino acids gaining recognition for their ability to promote relaxation and healthy sleep habits. L-Theanine, in particular, is known for its anti-stress effects; the amino acid is found in green tea and has been highlighted in various studies for its beneficial effects on both cognition and mood.

4. Method of Consumption: Each bottle comes with 60 capsules; the recommended serving size is 2 capsules, to be taken 30 to 60 minutes before bedtime.

5. Price: Luna is priced at $18.95 for a bottle containing 30 servings. There’s also a 100% money-back lifetime guarantee—if you’re not getting results, you don’t have to pay.

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About Nested Naturals Luna

Nested Naturals Luna is an ideal herbal remedy for those seeking improved sleep without breaking the bank. “I’ve always had trouble sleeping and finding this product helped me function so much better now than I’m sleeping every night.”—Luna review.

Positives
  • Another potential best GABA supplement for sleep.
Concerns
  • Its user ratings are slightly lower than other supplements on this list; on Amazon, it has under 4 stars, with some complaints about taste or other unfortunate side effects.

Best melatonin-free product

3.8 (880+) FROM AMAZON

Neuriva Relax & Sleep
  • Special Ingredients: L-theanine and Shoden® ashwagandha
  • Sourcing: Melatonin free, non-GMO, vegetarian, free from artificial flavors, colors, and preservatives.
  • Targeted Benefits: Formulated to help relax from daily stressors, improve overall sleep quality once asleep, and wake up feeling refreshed
  • Cost: Moderately priced ($$)
  • Customer Rating:3.8 out of 5.0 stars
  • Our Expert Rating: 4.1 out of 5.0 stars

*Price is accurate as of the date of publication.

The Review

1. Ingredients: Neuriva Relax & Sleep is a melatonin-free supplement, making it the only such supplement on this list. Its formula contains just two active ingredients: L-theanine and shoden ashwagandha. (The latter is a high-potency ashwagandha extract derived from the plant’s roots and leaves.)

2. Targeted Benefits: The combination of L-theanine and shoden ashwagandha aims to help you relax from daily stressors, improve overall sleep quality once asleep, and wake up feeling refreshed.

3. Medical Research: In recent years, more research has gone into the effects of ashwagandha, particularly shoden ashwagandha, on sleep. In 2020, the first human study on using ashwagandha extract for sleep was undertaken—a 72% increase in sleep quality was found for the treatment group, compared to just 29% in the placebo group. More research has occurred in the years that followed, with the majority showing that ashwagandha significantly reduced stress and anxiety levels, as well as sleeplessness, fatigue, and stress hormones.

4. Method of Consumption: Neuriva Relax & Sleep comes in capsule format. Just one capsule is recommended per day, to be taken 30 to 60 minutes ahead of bedtime.

5. Price: These capsules won’t break the bank, coming in at just $15.75 per bottle. Each bottle contains 30 capsules. Of note: Neuriva does not have a money-back guarantee.

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About Neuriva Relax & Sleep

Neuriva Relax & Sleep goes against the grain in that it doesn’t contain any melatonin. “This product helps me wake up refreshed and ready for the day.”—Neuriva review.

Positives
  • For those who may be sensitive to melatonin, this is a great melatonin-free option.
Concerns
  • High doses of ashwagandha, as found in shoden ashwagandha extract, have caused gastrointestinal distress and excess fatigue in some users.

Best serotonin support

4.4 (6.3K+) FROM AMAZON

NatureWise 5-HTP
  • Special Ingredients: Vitamin B6 and L-5-Hydroxy Tryptophan
  • Sourcing: Non-GMO, gluten-free, vegan, and contains no artificial fillers
  • Targeted Benefits: Aims to boost mood and reduce stress, act as a natural sleep aid, and curb cravings
  • Cost: Budget-friendly ($)
  • Customer Rating: 4.4 out of 5.0 stars
  • Our Expert Rating: 4.2 out of 5.0 stars

*Price is accurate as of the date of publication.

The Review

1. Ingredients: Within NatureWise 5-HTP are two active ingredients: vitamin B6 and L-5-Hydroxy Tryptophan, otherwise known as 5-HTP.

2. Targeted Benefits: NatureWise 5-HTP aims to boost mood and reduce stress, act as a natural sleep aid, and curb cravings.

3. Medical Research: The effects of 5-HTP, an amino acid involved in the production of serotonin—a chemical in the brain that plays a key role in a variety of bodily functions, including mood, sleep, digestion, nausea, wound healing, bone health, blood clotting, and sexual desire—are well known in research circles. In one study from 2021, subjects who took 5-HTP went to sleep far more quickly and slept more deeply than those who took a placebo. Meanwhile, vitamin B6 is crucial for brain development and maintaining healthy nervous and immune systems.

4. Method of Consumption: NatureWise 5-HTP is available in capsule form, with options of 100 milligrams or 200 milligrams of 5-HTP. One capsule is recommended for both doses.

5. Price: These supplements are offered in 60-count or 120-count bottles and 100-milligram or 200-milligram dosages. The 60-count bottles of both dosages are $19.29 ($0.32/capsule), while the 120-count bottles are particularly economical at just $19 ($0.16/capsule).

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About NatureWise 5-HTP

NatureWise 5-HTP emphasizes L-5-hydroxy-tryptophan, an amino acid that helps produce serotonin, which “promotes a calm and positive mood…and encourages healthy sleep patterns.”

Positives
  • The price for the 120-count bottles is a real deal for those on a budget.
  • While primarily a non habit forming sleep aid, the potential benefits may go beyond helping sleep.
Concerns
  • Exceeding the recommended dosage could be unsafe—large doses have been linked to severe stomach problems and muscle spasms.

Best for quick sleep onset

4.3 (617+) FROM AMAZON

  • Special Ingredients: Organic ashwagandha root, magnolia bark, organic passionflower flowering vine, and organic jujube date fruit and seed
  • Sourcing: Vegan, dairy & gluten-free & proudly made in NC, USA
  • Targeted Benefits: Aims to promote restful sleep during occasional bouts of sleeplessness
  • Cost: Higher price range ($$$)
  • Customer Rating: 4.3 out of 5.0 stars
  • Our Expert Rating: 4.4 out of 5.0 stars

*Price is accurate as of the date of publication.

The Review

1. Ingredients: Gaia Herbs uses a proprietary extract blend in its SleepThru supplement. Its key ingredients are organic ashwagandha root, magnolia bark, organic passionflower flowering vine, and organic jujube date fruit and seed.

2. Targeted Benefits: This supplement has one main goal: to promote restful sleep during occasional bouts of sleeplessness.

3. Medical Research: One study in rats found that passionflower extracts significantly increased deep sleep, reduced REM sleep, and facilitated quicker sleep onset. In humans, a study looking into passionflower tea found that it had short-term benefits in sleep quality. Both jujube fruit extract and magnolia have been used in traditional medicine for mild anxiety, nervousness, and sleep issues.

4. Method of Consumption: This supplement comes in capsule form, with a recommended intake of 2 capsules 1 hour before bedtime. According to Gaia Herbs, the best results are seen after one month of use.

5. Price: These are on the pricier side, with a 60-capsule bottle coming in at around $29 dollars ($0.48/capsule). There are also 30-count bottles on offer, which will run you back about $16 ($0.54/capsule) and only last 15 days, assuming you take two per day.

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About Gaia Herbs SleepThru

Gaia Herbs SleepThru places herbs and organic extracts at the fore. Its formula is gentle but has the potential to pack a sleepy punch and may provide “support for when the list in your head keeps you awake at night.”

Positives
  • This is among the most natural sleep supplements you’ll find.
Concerns
  • Among the other ingredients included is vegetable glycerin, which may be a cause for concern for some.
  • The price may be a barrier to entry for some.

Best proprietary ingredient for sleep

3.3 (17.7K+) FROM AMAZON

  • Special Ingredients: Magnesium, L-tryptophan, ashwagandha, GABA, chamomile, passionflower, melatonin, valerian root extract, and hops extract
  • Sourcing: Made in the U.S.A., drug-free, gluten-free, vegan
  • Targeted Benefits: Marketed to help you fall asleep, stay asleep, and wake feeling rested and ready for the day
  • Cost: Higher price range ($$$)
  • Customer Rating: 3.3 out of 5.0 stars
  • Our Expert Rating: 4.0 out of 5.0 stars

*Price is accurate as of the date of publication.

The Review

1. Ingredients: The key ingredients within Relaxium Sleep are magnesium, L-tryptophan, ashwagandha, GABA, chamomile, passionflower, melatonin, and Valerest, a proprietary blend of valerian root extract and hops extract.

2. Targeted Benefits: Relaxium Sleep claims to help you fall asleep, stay asleep, and wake feeling rested and ready for the day. Given that sleep deprivation can suppress the body’s immune system, the company also claims that it may very well boost immune health.

3. Medical Research: While there’s not yet third-party research on Valerest, the ingredients in its blend—valerian root extract and hops extract—do have some studies to support their efficacy. Multiple studies indicate that valerian root may reduce the amount of time it takes to fall asleep and improve sleep quality overall, while early research on hops—the female flowers from the hop plant that are most commonly found in beer—show that they do have sedative effects.

4. Method of Consumption: Relaxium Sleep comes in capsule form; two capsules should be taken at night before sleep.

5. Price: Another more expensive option, these come in at $35 a bottle, with each bottle containing 60 capsules (a 1-month supply). That puts each capsule around $0.58.

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About Relaxium Sleep

Relaxium Sleep sets itself apart from the rest by offering a proprietary ingredient within its stacked formula. “I’ve had insomnia my whole life, and these relax me and get me to rest every single night.”—Relaxium review.

Positives
  • The active ingredients in this supplement are tried-and-true and plentiful.
  • There may be benefits beyond sleep, including immune system support.
Concerns
  • It’s a pricier option compared to others on this list.

Best for getting the most active ingredients

4.0 (3.4K+) FROM AMAZON

  • Special Ingredients: Melatonin, L-Theanine, passionflower extract, valerian root extract, 5-HTP, vitamin B6, magnesium, lemon balm extract, GABA, and chamomile leaf extract
  • Sourcing: Made in the U.S.A with global ingredients, non-GMO, veggie capsules, vegan-friendly
  • Targeted Benefits: Marketed to support better sleep, brain function, and mood regulation
  • Cost: Moderately priced ($$)
  • Customer Rating: 4.0 out of 5.0 stars
  • Our Expert Rating: 4.4 out of 5.0 stars

*Price is accurate as of the date of publication.

The Review

1. Ingredients: Medchoice’s 10-in-1 sleep supplement contains a blend of ingredients, including melatonin, L-Theanine, passionflower extract, valerian root extract, 5-HTP, vitamin B6, magnesium, lemon balm extract, GABA, and chamomile leaf extract. A total of 1147 milligrams of active ingredients are in each supplement.

2. Targeted Benefits: Among Medchoice’s touted benefits are better sleep, brain function, and mood regulation.

3. Medical Research: Many of Medchoice’s ingredients have been studied in both animals and humans, demonstrating improved sleep. The supplement’s high melatonin content (6 milligrams per capsule) makes it one of the more melatonin-focused supplements on this list as well; the best melatonin supplements have been widely studied for their positive effects on sleep.

4. Method of Consumption: Medchoice is in capsule form; two should be taken at least an hour before bedtime.

5. Price: At $25 a 90-count pack, these capsules are firmly in the mid-range in terms of price point.

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About Medchoice 10-in-1 Natural Sleep Aid

Medchoice 10-in-1 Natural Sleep Aid has a laundry list of active ingredients that may very well help with both brain function and mood and “are for adults who want a non-habit forming way of getting a good night’s sleep,” according to the company.

Positives
  • For those who want the best melatonin sleep supplement, this sleep aid might do the trick.
Concerns
  • Taking two capsules might not sit well with those who don’t like sticking to a strict schedule.

Best valerian root product

4.0 (980+) FROM AMAZON

Jarrow Formulas Sleep Optimizer
  • Special Ingredients: Valerian root, L-Tryptophan, hops strobile complex, lemon balm leaf complex, GABA, and trace amounts of melatonin
  • Sourcing: Scienced-backed ingredients, suppliers are cGMP-compliant
  • Targeted Benefits: Marketed to help support healthier sleep cycle, increased relaxation, and a reduction in the time it takes to fall asleep
  • Cost: Moderately priced ($$)
  • Customer Rating: 4.0 out of 5.0 stars
  • Our Expert Rating: 4.1 out of 5.0 stars

*Price is accurate as of the date of publication.

The Review

1. Ingredients: This supplement contains valerian root (400 milligrams, to be exact), L-Tryptophan, hops strobile complex, lemon balm leaf complex, GABA, and trace amounts of melatonin.

2. Targeted Benefits: The company claims that with time, its supplement will lead to a healthier sleep cycle, increased relaxation, and a reduction in the time it takes to fall asleep.

3. Medical Research: Both valerian and hops have been associated with reducing the time it takes to fall asleep.

4. Method of Consumption: Sleep Optimizer comes in capsule form; the recommended dosage is two before bed or as directed by a healthcare professional.

5. Price: Another mid-range option, these go for just over $15 for a 60-pack of capsules.

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About Jarrow Formulas Sleep Optimizer

Jarrow Formulas Sleep Optimizer is a vegan supplement that “combines herbs and amino acids to help you fall asleep and support a regular sleep cycle.”

Positives
  • The company backs its formula with steadfast scientific research.
Concerns
  • As with some others on this list, taking two capsules every day may not be suitable for everyone.

Best non-capsule option

4.4 (7.1K+) FROM AMAZON

SugarBear Sleep Aid Gummies
  • Special Ingredients: Vitamin B6, L-Theanine, melatonin, 5-HTP, lemon balm leaf extract, blue passionflower extract, and valerian root
  • Sourcing: Made in the U.S.A., free of artificial sweeteners and flavors, certified vegan, cruelty-free
  • Targeted Benefits: Aims to promote rest, relaxation, and the deepest of sleep
  • Cost: Higher price range ($$$)
  • Customer Rating: 4.4 out of 5.0 stars
  • Our Expert Rating: 4.5 out of 5.0 stars

*Price is accurate as of the date of publication.

The Review

1. Ingredients: These gummies are chock-full of vitamin B6, L-Theanine, melatonin, 5-HTP, and a proprietary Rest Well Blend that includes lemon balm leaf extract, blue passionflower extract, and valerian root.

2. Targeted Benefits: These are designed for rest, relaxation, and the deepest of sleep.

3. Medical Research: Everything from melatonin to the ingredients within the proprietary Rest Well Blend has scientific studies backing up its efficacy.

4. Method of Consumption: These gummies are to be taken before bed, with a recommended intake of two gummies per night.

5. Price: Given that these are gummies, they’re on the pricier side, falling in at $35 for a month’s supply of 60 gummies.

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About SugarBear Sleep Aid Gummies

SugarBear Sleep Aid Gummies are the sole non-capsule sleep supplement option on this list. “These work amazing! Within 30 minutes I’m pretty much dead to the world and sleep perfectly.”—SugarBear review.

Positives

The gummy format may appeal to those who want a flavorful option.

Concerns
  • These contain tapioca syrup and cane sugar and have 15 calories per serving.

Best sleep supplement overall of the top 10: myPEAK DeltaSleep

All ten of these sleep supplements have been highly rated and reviewed; if you’re struggling with insomnia or poor sleep quality, any one of these has the potential to support better sleep. That said, one brand is the cream of the crop: myPEAK DeltaSleep.

While sleeping medications like Ambien can result in dependency and interfere with natural rhythms, myPEAK DeltaSleep is formulated to work with the body’s natural systems, minimizing the likelihood of interference with hormones or the brain’s chemistry.

A series of user reviews point to notable positive results yielded from myPEAK DeltaSleep, namely in that they feel well-rested and ready for each new day following a night with the deep sleep supplement. Many users also reported continuous, uninterrupted sleep throughout the night. The active ingredients speak for themselves, and while it may not be the cheapest option, it won’t break the bank, either.

Further reading:

Sleep Doctor: GABA for Sleep: Dosage and Side Effects

Sleep Foundation: Natural Sleep Aids

John Hopkins Medicine: Melatonin for Sleep: Does It Work?

 

Important Note: The information contained in this article is for general informational purposes only, and should not be construed as health or medical advice, nor is it intended to diagnose, prevent, treat, or cure any disease or health condition. Before embarking on any diet, fitness regimen, or program of nutritional supplementation, it is advisable to consult your healthcare professional in order to determine its safety and probable efficacy in terms of your individual state of health.

Regarding Nutritional Supplements Or Other Non-Prescription Health Products: If any nutritional supplements or other non-prescription health products are mentioned in the foregoing article, any claims or statements made about them have not been evaluated by the U.S. Food and Drug Administration, and such nutritional supplements or other health products are not intended to diagnose, treat, cure, or prevent any disease.

Manufacturers And Distributors:

Manufacturers And Distributors: We hope that you enjoyed this article and found it informative. If your company, brand, or product was featured in this article and you believe that our assessment or evaluation was not fully accurate, or if your company, brand, or product was not mentioned in this article and you think that it should have been included, please let our editorial staff know about it! Contact us at [email protected].

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