Home VITAMINS, MINERALS & SUPPLEMENTS Vitamin C: Benefits, Dosage, Side Effects, Drug Interactions, and Other Important Information

Vitamin C: Benefits, Dosage, Side Effects, Drug Interactions, and Other Important Information

by Steve Schapiro
Vitamin C

The multiple health advantages of vitamin C, commonly known as ascorbic acid, a water-soluble vital nutrient, have been thoroughly investigated. There is rising interest in vitamin C’s potential as a nootropic, particularly in relation to its role in boosting memory, learning, and cognition. Vitamin C’s antioxidant and immune-boosting qualities are widely known as well. This article examines the chemistry of vitamin C, and its physiological functions, and offers advice on how to use it safely, with a focus on improving cognition.

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Nature of Vitamin C

Vitamin C is a water-soluble, essential nutrient needed by the body for many physiological functions. The human body cannot produce vitamin C, making it an essential component that must be consumed by diet or supplementation. It is present in a variety of fruits and vegetables, with citrus fruits, strawberries, kiwifruit, bell peppers, and cruciferous vegetables like broccoli and brussels sprouts having some of the greatest quantities.

Vitamin C is a potent antioxidant that can counteract dangerous free radicals, shielding cells from oxidative stress and damage. Because it is water-soluble, it may easily be absorbed and dispersed throughout the body, including the brain, where it is found in high amounts. Vitamin C has a special quality that allows it to have a variety of positive impacts on mental and physical health.

Strawberries.

Health Benefits of Vitamin C

Vitamin C has a long list of cognitive advantages in addition to its well-known function in the immune system, including:

1. Mood enhancer: An improved mood and decreased anxiety have been linked to vitamin C supplementation in studies on both healthy people and people with mood disorders.

2. Improved concentration and alertness: Vitamin C can aid with focus, attention, and general cognitive performance by encouraging the synthesis of dopamine and norepinephrine.

3. Protection against cognitive decline: Being a potent antioxidant and neuroprotective agent, vitamin C can help retain cognitive function and prevent the start of age-related cognitive decline.

Dopamine sources.

Chemistry of Vitamin C

Glucose is the source of the six-carbon ascorbic acid (C6H8O6). Due to its hydrophilic and lipophilic characteristics, this highly polar molecule may dissolve in both lipids and water. Because of this special quality, vitamin C may easily pass through cell membranes and affect a variety of tissues, including the brain. Its ability to readily donate electrons, which neutralizes free radicals and shields cells from oxidative damage, is the source of its antioxidant effects.

Physiological Mechanism of Action of Vitamin C

Many physiological functions, including collagen production, wound healing, and the metabolism of neurotransmitters, depend on vitamin C. With relation to cognitive function, vitamin C is present in the brain at high concentrations and plays a role in a number of important neurological functions, including:

1. Antioxidant properties: Vitamin C works as an antioxidant to prevent reactive oxygen species (ROS) and reactive nitrogen species from damaging neural cells. Vitamin C helps to maintain overall brain health by disarming these dangerous chemicals and preserving the structural and functional integrity of neurons.

2. Synthesis of neurotransmitters: Vitamin C functions as a cofactor for enzymes that produce neurotransmitters like dopamine, norepinephrine, and serotonin. These neurotransmitters play a crucial role in controlling mood, focus, and cognitive ability. Vitamin C can help with their production, which in turn helps with cognitive function.

3. Neuroprotection: Studies have shown that vitamin C reduces neuronal inflammation, regulates neurotransmitter systems, and lessens the buildup of harmful proteins in the brain, protecting against neurodegenerative disorders like Alzheimer’s and Parkinson’s.

Collagen.

Optimal Dosage of Vitamin C

For adult men, the recommended dietary amount (RDA) for vitamin C is 90 mg/day while for adult women it is 75 mg/day. Nevertheless, dosages in the range of 250-500 mg/day have been recommended for nootropic purposes to maximize cognitive advantages without producing negative effects.

Side Effects of Vitamin C

Because of its water solubility and rapid excretion from the body, vitamin C is generally regarded as safe, even at higher doses. However, excessive consumption may result in the following side effects:

1. Gastrointestinal discomfort: Excessive vitamin C consumption can result in diarrhea, nausea, and stomach cramps.

2. Kidney stones: Too much vitamin C may increase the risk of developing kidney stones, especially in people who are predisposed to this condition.

3. Iron overload: Because vitamin C increases iron absorption, it can lead to iron overload in people who are predisposed to it, such as those with hemochromatosis.

A boy is doing exercise.

Potential Substance Interactions with Vitamin C

Vitamin C may interact with the following medications and substances:

1. Anticoagulants: High doses of vitamin C may impair the effectiveness of anticoagulant medications such as warfarin by interfering with the drug’s metabolism.

2. Chemotherapy drugs: Because vitamin C has been shown to reduce the efficacy of some chemotherapy drugs, it is critical to consult with a healthcare professional before taking vitamin C supplements during cancer treatment.

3. Statins: Because vitamin C may reduce the effectiveness of cholesterol-lowering statin drugs, people who take them should consult their doctor before taking vitamin C supplements.

A cancer patient consulting to a doctor.

Best Responsible Use of Vitamin C

To fully realize vitamin C’s cognitive-enhancing potential, it is critical to follow the following guidelines for responsible use:

1. Select a product of high quality and bioavailability: To maximize the cognitive benefits of vitamin C, choose a supplement with optimal absorption and efficacy. myPEAK Radiance, available from myPEAK Supplements, is an excellent choice because it combines vitamin C with other synergistic nootropic ingredients in a highly bioavailable formulation designed to support brain health and focus.

2. Consult a healthcare professional: It is best to consult with a healthcare professional before beginning a vitamin C supplementation regimen for cognitive enhancement, especially if you are taking medications that may interact with vitamin C or have pre-existing health conditions.

3. Eat a well-balanced diet: Include plenty of vitamin C-rich fruits and vegetables in your diet, as they provide additional micronutrients and phytochemicals that can help with overall health and cognitive function.

Vitamin C:

Conclusion

Vitamin C is one of the most common supplements used by the general public to prevent illness and maintain their overall health. Vitamin C has been linked with improved mood and motivation and it also helps retain cognitive ability with continuous and consistent use of this supplement. This is because many metabolic pathways which involve neurological function depend on vitamin C. Very high doses of vitamin C are generally regarded as safe but you still need to note the dosage that you are taking daily. Overdose of this vitamin may lead to kidney stones and iron overload. Speak with your doctor to find out the best dosage for you and source this vitamin from trustworthy sellers like myPEAK supplements.

References

  1. Vitamin C Intake and Multiple Health Outcomes: An Umbrella Review of Systematic Reviews and Meta-Analyses. Link: https://pubmed.ncbi.nlm.nih.gov/35291895/
  2. Vitamin C in Disease Prevention and Cure: An Overview. Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783921/
  3. The Health Effects of Vitamin C Supplementation: A Review. Link: https://pubmed.ncbi.nlm.nih.gov/7790686/

Important Note: The information contained in this article is for general informational purposes only, and should not be construed as health or medical advice, nor is it intended to diagnose, prevent, treat, or cure any disease or health condition. Before embarking on any diet, fitness regimen, or program of nutritional supplementation, it is advisable to consult your healthcare professional in order to determine its safety and probable efficacy in terms of your individual state of health.

Regarding Nutritional Supplements Or Other Non-Prescription Health Products: If any nutritional supplements or other non-prescription health products are mentioned in the foregoing article, any claims or statements made about them have not been evaluated by the U.S. Food and Drug Administration, and such nutritional supplements or other health products are not intended to diagnose, treat, cure, or prevent any disease.

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