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Home Anxiety Top 8 Best Natural Supplements For Anxiety: In-Depth Reviews

Top 8 Best Natural Supplements For Anxiety: In-Depth Reviews

by Lawrence D Jones
best natural supplements for anxiety

On This Page

Levium is our top pick of the best natural supplements for anxiety, with OLLY Ultra Goodbye Stress Softgels, Les Labs Cortisol Health, and Nature Made Wellblends Calm & Relax trailing close behind. Read on for the full list, plus tips for choosing the best natural supplements for anxiety to meet your specific needs.

A quick look at the best natural supplements for anxiety

Are you struggling with sleep disturbances? Is the thought of taking a break hindered by financial and personal commitments? Fortunately, there is a range of options available to address these challenges, including over the counter anxiety medication, supplements designed to alleviate stress, and various anxiety relief products. Many of these anxiety relief products and stress-alleviating supplements are derived from natural ingredients and are recognized within the healthcare community for their potential to effectively reduce anxiety and stress. Considering the foregoing, our selection for the best overall product is LEVIUM.

Understanding anxiety

Anxiety affects millions of Americans, and it can make life really difficult. Many people use prescription drugs to cope with it, but these often bring unwanted side effects. There are natural options out there that are gaining attention as helpful solutions for anxiety. In this article, we will look into how they may reduce anxiety, boost your mood, improve your thinking, help you sleep better, and even aid in weight loss.

In selecting the best natural supplements for anxiety, we’ve considered the ingredients, assessing their natural origins and potential benefits. Sourcing and quality control are paramount in our evaluation, examining the manufacturing processes to guarantee purity and potency. Form and dosage play a crucial role in the effectiveness of supplements, and we’ve scrutinized these aspects for each product. Additionally, real-world user experiences matter, so we’ve incorporated reviews to provide insights into the practical effects of these supplements.

Please appreciate that these products have not received FDA approval for their role as a preventive or therapeutic measure for these conditions; however, they have the potential to serve as a valuable complement to traditional healthcare or medical procedures employed in the prevention or treatment of these ailments.

Consider routine anxiety screening

Regularly monitoring your anxiety is not just about understanding the issue; it is about discovering a wealth of strategies to confront anxiety proactively. This encompasses a range of options, from prescribed medications to over the counter remedies and soothing supplements. Embracing this proactive approach empowers you to manage anxiety effectively, enhancing your mental and emotional well-being.

It’s important to note that anxiety relief products can have varying effects on individuals. Therefore, it’s crucial to consult with a healthcare professional before incorporating any new dietary supplement into your regimen, particularly if you have preexisting health conditions or are currently taking other medications.

HealthXWire's picks of the best natural supplements for anxiety

Best overall

4.5 (1.9K+) FROM LEVIUM

Levium
  • Special Ingredients: Resveratrol, ashwagandha, GABA, niacin, luteolin, apigenin
  • Sourcing: USP compliant, cGMP compliant
  • Targeted Benefits: Conteracting cortisol
  • Cost: Higher price range ($$$)
  • Customer Rating: 4.5 out of 5.0 stars
  • Our Expert Rating: 4.8 out of 5.0 stars

*Price is accurate as of the date of publication.

Reviewing Levium

1. Ingredients: Levium contains natural ingredients with anti-inflammatory, antioxidant, and neuroprotective properties. The components of Levium, in particular resveratrol, ashwagandha, GABA, niacin, and luteolin, are claimed to work potentially synergistically to reduce the feeling of anxiety.

2. Targeted Benefits: According to Dr. David Kipper, Levium’s Clinical Director, Levium works by counteracting cortisol – commonly known as the stress hormone – which is responsible for many symptoms associated with anxiety.

3. Sourcing and Quality Control: All raw materials that go into the production of Levium comply with stringent USP or similar monographs. In addition, Levium asserts that final capsule production is in accordance with cGMP (current Good Manufacturing Practices) guidelines as promulgated under 21 CFR § 211.

4. Dosage Form: A convenient 90-count monthly supply is packaged in a travel-friendly bottle. Slow-release capsules are designed to offer daily relief within a single dosage. Three capsules constitute one dose. The product is manufactured in the United States within an FDA-inspected facility.

5. Reviews: MarketWatch, a leading business news and financial information website, announced on October 25, 2023, in a Levium Review: “LEVIUM, a natural anxiety relief supplement […] has won the award for Best Non-Prescription Stress and Anxiety Relief Supplement from Optimal Performance Living, a digital publication. LEVIUM's unique formulation promises quick relief from stress and anxiety with no side effects, using natural, clinically proven ingredients that are non-addictive and safe to use with common prescription medications.” Multiple reviews and comments on Amazon support Levium's claims of anxiety relief. The product maintains a rating of 4.5 out of 5.0 from 1,924 reviews on their website.

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About Levium Supplements

Christopher Adams is the CEO and Founder of multiple successful startups. He also established Glauser Life Sciences, the creator of Levium, designed to assist individuals dealing with central nervous system disorders, including anxiety. According to Christopher, "Glauser Life Sciences, Inc. is committed to pioneering what we consider to be groundbreaking, next-generation therapies for a wide range of Central Nervous System (CNS) disorders." Levium represents his commitment to this vision.

Positives
  • Formulated to help reduce cortisol levels and increase GABA levels, which are associated with stress and anxiety.
  • Levium may improve sleep quality, mood, focus, decision-making, and creativity by enhancing neuronal formation and blood flow in the brain.
  • Levium has a money-back guarantee for first-time buyers of single, entry-level products.
Concerns
  • It is not yet sold in offline retail stores.
  • The product is slightly more expensive than most of its competitors.

4.3 (8.0K+) FROM AMAZON

OLLY Ultra Goodbye Stress Softgels
  • Special Ingredients: GABA, L-theanine, Lemon Balm, ashwagandha
  • Sourcing: USP compliant, FDA compliant
  • Targeted Benefits: Enhance neuronal formation and blood flow in the brain
  • Cost: Moderately priced ($$)
  • Customer Rating: 4.3 out of 5.0 stars
  • Our Expert Rating: 4.4 out of 5.0 stars

*Price is accurate as of the date of publication.

Reviewing OLLY Ultra Goodbye Stress Softgels

1. Ingredients: OLLY Ultra Goodbye Stress Softgels contain natural ingredients that have been shown to support a relaxed state of mind, such as GABA, L-Theanine, Lemon Balm, and Ashwagandha.

2. Targeted Benefits: OLLY Ultra Goodbye Stress Softgels may also improve your mood, energy, sleep quality, creativity, and cognitive function by enhancing neuronal formation and blood flow in the brain.

3. Sourcing and Quality Control: All raw materials that go into the production of OLLY Ultra Goodbye Stress Softgels comply with the USP or similar monographs.  In addition, OLLY asserts that final capsule production is in accordance with FDA guidelines.

4. Dosage Form: They recommend taking two softgels per day with water as needed, swallow whole and do not chew. The supplement comes with 60 capsules per bottle for a 30-day supply. The product is manufactured in the United States within an FDA-inspected facility.

5. Reviews: Multiple reviews and comments on Amazon support OLLY Ultra Goodbye Stress Softgels' claims of anxiety relief. The product has a cumulative rating of 4.3 out of 5.0 from 8,011 Amazon reviews.

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About OLLY Vitamins

In 2019, Unilever successfully completed the acquisition of OLLY, a vitamin brand headquartered in San Francisco. Unilever boasts a diverse portfolio of brands, including Pukka Herbs, Ren Skincare, and Graze. OLLY was co-founded in 2014 by Eric Ryan and Brad Harrington.

OLLY's gummy supplement range is predominantly produced in the United States, with the exception of select products manufactured in Colombia. Additionally, OLLY Ultra Goodbye Stress Softgels are all manufactured within the United States.

Positives
  • OLLY Ultra Goodbye Stress Softgels work fast, within 30 to 60 minutes, to help you cope with stress without making you drowsy.
Concerns
  • Of over 7,000 Amazon reviews, approximately 20% are negative, with complaints about lack of efficacy or side effects.
  • OLLY Ultra Goodbye Stress Softgels may interact with some medications, such as antidepressants, anticonvulsants, or blood thinners. Therefore, it is advisable to consult a doctor before taking OLLY Ultra Goodbye Stress Softgels.

Best natural relief

4.2 (7.8K+) FROM AMAZON

  • Special Ingredients: Phosphate salts of calcium, iron, magnesium, sodium, and potassium
  • Sourcing: FDA compliant, cGMP compliant
  • Targeted Benefits: Mood, energy, sleep quality, and cognitive function improvement
  • Cost: Moderately priced ($$)
  • Customer Rating: 4.2 out of 5.0 stars
  • Our Expert Rating: 4.2 out of 5.0 stars

*Price is accurate as of the date of publication.

Reviewing Hyland’s Naturals Calm

1. Ingredients: Hyland’s Naturals Calm contains the phosphate salts of calcium, iron, magnesium, sodium, and potassium. Each of these naturally occurring salts is recorded in the literature as potentially alleviating anxiety and stress.

2. Targeted Benefits: Hyland’s Naturals Calm claims mood, energy, sleep quality, and cognitive function improvement.

3. Sourcing and Quality Control: Hyland’s Naturals Calm is produced within a state-of-the-art facility that adheres to FDA regulations and complies with cGMP standards.

4. Dosage Form: Gentle-to-ingest tablets designed to alleviate stress and support natural sleep. Each box of Hyland's Naturals Calm contains 50 tablets, providing up to 50 doses. The supplement is free from artificial flavors, sugars, dyes, or parabens.

5. Reviews: Hyland's Naturals Calm maintains a rating of 4.2 out of 5.0 from 7,874 Amazon reviews.

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About Hyland's

The company, initially established in Los Angeles in 1903 under the name Standard Homeopathic Pharmacy, underwent a change in ownership when George H. Hyland acquired it in 1910. Subsequently, the company's name was modified to Standard Homeopathic Company. Hyland's expansion into the Canadian market took place in 1990, marking a significant milestone in their history.

Positives
  • Contains natural ingredients that have anti-inflammatory, antioxidant, and neuroprotective properties.
  • Hyland’s Natural Calm has a money-back guarantee for first-time buyers of single, entry-level products.
Concerns
  • Many of the claims made by manufacturers of homeopathic medications need to be scientifically proven in order to be advertised.
  • Hyland’s Natural Calm may not work for everyone, as some users reported no noticeable effects or benefits from taking the supplement.

Best vegan capsules

4.4 (2.3K) FROM AMAZON

NOW True Calm
  • Special Ingredients: GABA, magnesium, glycine, inositol
  • Sourcing: In-house laboratories, instruments, and staff
  • Targeted Benefits: Neurotransmitter support, promotes relaxed mood 
  • Cost: Budget-friendly ($)
  • Customer Rating: 4.4 out of 5.0 stars
  • Our Expert Rating: 4.2 out of 5.0 stars

*Price is accurate as of the date of publication.

Reviewing True Calm

1. Ingredients: True Calm is a synergistic blend of GABA, magnesium, glycine, inositol, and their cofactor nutrients carefully designed to bolster the typical generation and operation of soothing neurotransmitters within the brain.

2. Targeted Benefits: Their anxiety relief product incorporates GABA and glycine, both amino acids that foster a tranquil mental state, in addition to taurine, another non-essential amino acid recognized for its calming attributes. These nutrients are combined with Valerian, which is recognized for its interaction with the GABA receptors in the nervous system.

3. Sourcing and Quality Control: NOW maintains in-house laboratories, instruments, and staff that allow them to analyze faster, be more adaptive, and provide fresher products.

4. Dosage Form: The product is available in convenient 90-capsule quantities.

5. Reviews: The product has 2,339 ratings on Amazon, earning it a rating of 4.4 out of 5 stars.

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About NOW

During his early years, Elwood Richard, an entrepreneur and degreed physical chemist, established Health House, a chain of health food stores in Chicago. Over the years, this company grew into NOW. The CEO of NOW says, “The backbone of NOW and the reason for our ongoing success is, without question, our people. Everyone at NOW is continuously working to support our corporate mission – to provide value in products and services that empower people to lead healthier lives.”

Positives
  • Contains natural ingredients that support the normal production and function of calming neurotransmitters in the brain.
  • Now Foods True Calm includes GABA and glycine, two amino acids that promote a relaxed state of mind, along with taurine, another amino acid with calming properties.
  • Now Foods True Calm is vegan, gluten-free, non-GMO, and kosher certified.
Concerns
  • Based on an aggregate of reviews, its results vary greatly among users, as some customers mentioned experiencing little to no positive effects at all.
  • The Cleveland Clinic notes that products containing inositol, a form of sugar in the body, are likely safe when taken in low doses, but mild symptoms of diarrhea, nausea, abdominal pain, dizziness, and fatigue have been reported.

Best adaptogenic support

4.3 (3K+) FROM AMAZON

  • Special Ingredients: Ashwagandha, 5-HTP, L-Theanine, GABA, Magnesium, Rhodiola Rosea, Lemon Balm, Valerian Root, Gotu Kola
  • Sourcing: Manufactured under strict FDA guidelines
  • Targeted Benefits: Alleviate stress, anxiety, and boost mood
  • Cost: Higher price range ($$$)
  • Customer Rating: 4.3 out of 5.0 stars
  • Our Expert Rating: 4.1 out of 5.0 stars

*Price is accurate as of the date of publication.

Reviewing Zenium Tranquility

1. Ingredients: Zenium Tranquility contains Ashwagandha, 5-HTP, L-Theanine, GABA, Magnesium, Rhodiola Rosea, Lemon Balm, Valerian Root, Gotu Kola, and many other adaptogens.

2. Targeted Benefits: This product claims to alleviate stress and anxiety and boost mood using natural plant-based ingredients.

3. Sourcing and Quality Control: Zenium manufactures its products under strict FDA guidelines.

4. Dosage Form: The product is offered in convenient 60-capsule quantities.

5. Reviews: Over 3,000 ratings on Amazon have earned the product a rating of 4.3 out of 5.0

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About Zenium Labs

Zenium Labs was founded by Franek Sodzawiczny, who, after losing his partner, honored her by founding this company to help others struggling with anxiety. Zenium Tranquility is a nootropic supplement for stress from Zenium Labs. 

Positives
  • Contains natural ingredients that have anti-inflammatory, antioxidant, and neuroprotective properties.
  • Zenium Tranquility may help reduce anxiety, lessen tension, fight stress, improve mental outlook, and boost mood by modulating neurotransmitters and hormones that are associated with stress and anxiety.
  • Zenium Tranquility has a money-back guarantee for first-time buyers of single, entry-level products.
Concerns
  • Zenium Tranquility is an expensive supplement, costing $26.65 for a 90-count bottle of capsules.
  • According to Center TRT, while some of these ingredients have potential benefits for anxiety, stress, and sleep disorders, most are included in doses too low to be effective.

Best for balanced cortisol response support

4.3 (7.7K+) FROM AMAZON

Les Labs Cortisol Health
  • Special Ingredients: Phosphatidylserine, ashwagandha root, magnesium
  • Sourcing: Compliant with FDA quality guidelines
  • Targeted Benefits: Promotes balanced cortisol response and restful sleep
  • Cost: Moderately priced ($$)
  • Customer Rating: 4.3 out of 5.0 stars
  • Our Expert Rating: 4.2 out of 5.0 stars

*Price is accurate as of the date of publication.

Reviewing Les Labs Cortisol Health

1. Ingredients: This product contains phosphatidylserine, Ashwagandha root, magnesium

2. Targeted Benefits: This product is marketed to promote balanced cortisol response and restful sleep.

3. Sourcing and Quality Control: Les Labs is compliant with FDA quality guidelines for the manufacture of this product.

4. Dosage Form: The product is available in convenient 60-capsule quantities.

5. Reviews: Over 7,000 ratings on Amazon have earned the product a rating of 4.3 out of 5.0

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About Les Labs

Les Labs was founded by John Heathco. John commented, “Unlike other brands, we don't chase trends or fads - we use our extensive knowledge and expertise to create the best products for you.” Accordingly, Les Labs Cortisol Health was developed. This company has carved a unique niche in the world of healthcare.

Positives
  • Targets cortisol levels to help individuals better manage stress and its associated symptoms.
  • Promotes balanced cortisol levels, which are associated with improved energy and mental alertness.
Concerns
  • While phosphatidylserine is necessary for good neuron health, Verywellmind recommends talking with a healthcare provider before considering products containing phosphatidylserine, especially if you are currently taking a blood thinner, antidepressant, antihistamine, or medication for glaucoma or Alzheimer's disease.
  • Cortisol levels can vary significantly from person to person, and what works for one individual may not be effective for another.

Best herbal blend

4.4 (990+) FROM AMAZON

  • Special Ingredients: Lavender, holy basil, skullcap, and oats
  • Sourcing: Adheres to FDA quality standards
  • Targeted Benefits: Supports a calm response to stressful situations and helps provide relief from occasional anxiousness
  • Cost: Higher price range ($$$)
  • Customer Rating: 4.4 out of 5.0 stars
  • Our Expert Rating: 4.5 out of 5.0 stars

*Price is accurate as of the date of publication.

Reviewing Gaia Herbs Calm A.S.A.P

1. Ingredients: The supplement contains lavender, holy basil, skullcap, and oats.

2. Targeted Benefits: Gaia Herbs Calm A.S.A.P is a natural supplement that supports a calm response to stressful situations and helps provide relief from occasional anxiousness.

3. Sourcing and Quality Control: Gaia Herbs adheres to FDA quality standards in the production of this product.

4. Dosage Form: The product is offered in convenient 60-capsule quantities.

5. Reviews: The product has a rating of 4.4 out of 5.0 from 988 Amazon reviews.

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About Gaia Herbs

Since its inception in 1987, Gaia Herbs has embraced its mission of promoting connections between people, plants, and the planet to facilitate healing. The organization recognized what is now widely acknowledged: the interconnected evolution of plants and humanity, intertwined destinies, and the essential wisdom for healing that resides within the plant realm.

Positives
  • Gaia Herbs Calm A.S.A.P contains an herbal blend featuring Passionflower, Chamomile, Vervain, English Lavender, and Holy Basil, which have anti-inflammatory, antioxidant, and neuroprotective properties.
  • Gaia-grown Skullcap and Oats are extracted fresh immediately after harvest to preserve full spectrum compounds for optimal potency.
  • Gaia Herbs Calm A.S.A.P is an award-winning formula for times of circumstantial stress and has a money-back guarantee for first-time buyers.
Concerns
  • Based on 988 Amazon reviews, 10 -15% posted negative opinions regarding the product.
  • Gaia Herbs Calm A.S.A.P may interact with some medications, such as antidepressants, anticonvulsants, or blood thinners. It is advisable to consult a doctor before taking Gaia Herbs Calm A.S.A.P.

4.5 (2.2K+) FROM AMAZON

  • Special Ingredients: Ashwagandha, magnesium
  • Sourcing: USP compliant
  • Targeted Benefits: Reduce stress and relax the body.
  • Cost: Moderately priced ($$)
  • Customer Rating: 4.5 out of 5.0 stars
  • Our Expert Rating: 4.2 out of 5.0 stars

*Price is accurate as of the date of publication.

Reviewing Nature Made Wellblends Calm & Relax

1. Ingredients: The supplement contains a 2-in-1 blend scientifically designed with ashwagandha and magnesium.

2. Targeted Benefits: Nature Made Wellblends Calm & Relax is formulated to help reduce stress and relax the body.

3. Sourcing and Quality Control: Nature Made is also committed to quality, science, and innovation and claims to have the most USP-verified products on the market.

4. Dosage Form: The product is available in a bottle containing 54 vegetarian capsules.

5. Reviews: The product has a rating of 4.5 out of 5.0 from 2,276 Amazon reviews.

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About Nature Made

Nature Made Wellblends Calm & Relax is manufactured and distributed by Pharmavite. Pharmavite, headquartered in California, is committed to promoting healthier and more vibrant lifestyles for individuals. Nature Made was founded in 1971 by Barry Pressman and Henry Burdick, who believed there was a better alternative to long-term health than prescription drugs.

Positives
  • Contains Sensoril Ashwagandha, a standardized herb that has been shown to reduce cortisol and perceived stress.
Concerns

Best overall of the Top 8: Levium

In evaluating the top natural supplements for anxiety, we have considered each product’s
ingredients, targeted benefits, sourcing and quality control, form and dosage, and reviews.
Despite the absence of FDA approval, the quality of these supplements attests to their
effectiveness. Within this category, a product truly distinguishes itself as not just a superior
over-the-counter anxiety medication but also an exceptional choice for managing stress:
LEVIUM.

Levium stands out due to its formulation, which incorporates a level of meticulously researched ingredients that surpasses those found in competing products. To clarify, when we say “researched,” we mean that recognized authorities have thoroughly examined these ingredients, both individually and, in some instances, in combination.

Furthermore, Levium comes highly recommended for several compelling reasons:

  • Efficacy: Levium’s unique blend of ingredients has been meticulously studied and selected to provide optimal relief from anxiety and stress.
  • Safety: The formulation is designed with safety in mind, adhering to rigorous quality and purity standards.
  • Trustworthiness: Levium has gained the trust of individuals seeking effective solutions for anxiety and stress management.
  • Expert Approval: Health experts and professionals have recognized Levium as a valuable option for those looking to address their anxiety and stress-related concerns.

Levium not only boasts a superior formulation but also receives strong endorsements due to its proven efficacy, safety, and the trust it has garnered from both experts and consumers.

 

Further reading:

UCLA Health: Routine screening for anxiety in asymptomatic adults recommended

Mayo Clinic: Anxiety disorders

Medical News Today: Treatments for Anxiety

Mass General Brigham: Treatment for Generalized Anxiety Disorder (GAD)

 

Important Note: The information contained in this article is for general informational purposes only, and should not be construed as health or medical advice, nor is it intended to diagnose, prevent, treat, or cure any disease or health condition. Before embarking on any diet, fitness regimen, or program of nutritional supplementation, it is advisable to consult your healthcare professional in order to determine its safety and probable efficacy in terms of your individual state of health.

Regarding Nutritional Supplements Or Other Non-Prescription Health Products: If any nutritional supplements or other non-prescription health products are mentioned in the foregoing article, any claims or statements made about them have not been evaluated by the U.S. Food and Drug Administration, and such nutritional supplements or other health products are not intended to diagnose, treat, cure, or prevent any disease.

Manufacturers And Distributors:

Manufacturers And Distributors: We hope that you enjoyed this article and found it informative. If your company, brand, or product was featured in this article and you believe that our assessment or evaluation was not fully accurate, or if your company, brand, or product was not mentioned in this article and you think that it should have been included, please let our editorial staff know about it! Contact us at [email protected].

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