Description
A hyperactive immune system that assaults the body’s healthy tissues is the hallmark of the complex autoimmune illness lupus. Lupus can impact a lot of organs, including the skin, kidneys, joints, lungs, heart, and brain. The symptoms of lupus range in intensity and frequency. Fatigue, joint discomfort, skin rashes, fever, photosensitivity, organ involvement, and the recognizable butterfly rash are the typical symptoms of lupus.
Due to the relapsing-remitting nature of lupus, symptoms might fluctuate as time passes. Systemic lupus erythematosus (SLE) is one of the various kinds of lupus that impacts numerous bodily organs and systems. Discoid lupus erythematosus (DLE) primarily affects the skin and causes discoid-shaped rashes. Neonatal lupus affects infants whose mothers suffer from lupus antibodies, whereas drug-induced lupus develops as an adverse effect of several drugs.
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Lupus: Description, Causes, and Treatment Protocol is an original (HealthXWire) article.
Possible Causes
According to research, genetics may contribute to lupus susceptibility, with some genes being linked to a higher risk. Environmental elements can cause or aggravate lupus symptoms, including UV exposure, infections, drugs, and hormones. During pregnancy, puberty, and menopause, hormonal changes can potentially affect the activity of diseases.
Exacerbating and Mitigating Factors
Certain cues or factors may exacerbate the patients’ conditions for lupus. This includes exposure to ultraviolet (UV) rays of sunlight, anticonvulsants and antibiotics, infections, mental or emotional stress, hormonal changes, smoking, and physical or emotional stress. These elements can cause lupus flare-ups by bringing on or exacerbating the condition’s symptoms. On the contrary, mitigating variables include controlling stress levels, obtaining enough sleep and rest, maintaining a balanced diet, limiting sun exposure, having regular physical activity, and following recommended drug regimens. The effects of lupus can also be lessened by having a strong support system, looking for emotional assistance, and taking part in activities that enhance mental health.
Standard Treatment Protocol
Nephrology, rheumatology, dermatology, and other related medical specialties are frequently used in the multidisciplinary approach to lupus treatment. Controlling symptoms, preventing organ damage, and enhancing the general quality of life are the main targets of treatment. The following elements may constitute part of the typical lupus treatment plan: –
Antimalarial Drugs: Lupus is typically treated with hydroxychloroquine (Plaquenil). It has preventive benefits on one’s skin and internal organs in addition to assisting in disease activity control. Antimalarial medications help lessen joint pain, lupus flare-up frequency, and skin rashes.
Nonsteroidal Anti-inflammatory Drugs (NSAIDs): NSAIDs can be used to alleviate pain, decrease inflammation and treat mild to moderate lupus symptoms. Examples of NSAIDs that are frequently prescribed by doctors are naproxen or ibuprofen which can be used to ease fever, aches in the muscles as well as discomfort in the joints.
Corticosteroids: Corticosteroids like prednisone may be administered in instances involving mild to extreme lupus activity. These potent anti-inflammatory drugs can help decrease disease activity and treat acute symptoms. Nevertheless, to the possibility of side effects, prolonged usage of corticosteroids must be avoided.
Biologic Therapies: Biologic therapy could be used in some circumstances. These medications can help control lupus activity by specifically targeting certain immune system components. Rituximab (Rituxan) and belimumab (Benlysta) are two examples of biological treatments that are used to treat lupus.
Immunosuppressants: Immunosuppressant medications may be used for lupus sufferers who have more severe cases or who do not react well to other therapies. These drugs inhibit the immune system and prevent it from attacking the organs. Examples of these drugs include cyclophosphamide, methotrexate, azathioprine, or mycophenolate mofetil.
Treatment Options
Numerous therapeutic approaches may be taken into account to support traditional therapies for lupus alongside the regular treatment plan. Prescription drugs, over-the-counter medicines, dietary supplements, and natural herbs are a few of these alternatives. While many of these options might have potential advantages, it is vital to remember to discuss their effectiveness and safety with medical experts. Several typical lupus treatment options include:
Over-the-Counter Formulations: Analgesics like acetaminophen along with topical ointments or creams like hydrocortisone cream might temporarily relieve mild lupus symptoms like rashes, pain, and itch. Nevertheless, it is essential to speak with a healthcare expert before utilizing these medications because they might interact with prescription pharmaceuticals or have negative effects on some people.
Nutritional Supplements: In addition to standard lupus treatment, nutritional supplements might prove beneficial. Certain supplements may offer extra advantages in treating symptoms and boosting general health, while they ought not to be used in place of prescription prescriptions. Before beginning any new supplements, it is essential to speak with a medical expert because they could interfere with certain prescriptions or have varying effects on different people. Following are a few dietary supplements with the potential for lupus management: –
- Antioxidants
Increased oxidative stress in lupus has been linked to disease activity. Vitamin C, vitamin E, selenium, alpha-lipoic acid, and other antioxidants can help lower oxidative damage and might provide anti-inflammatory benefits. These antioxidants may be received through a healthy diet or in the form of supplements, but the amounts taken should be set by a healthcare provider.
- Vitamin D
People with lupus frequently lack vitamin D, thus supplements may be recommended. Bone health and the functioning of the immune system are supported by sufficient vitamin D levels. Vitamin D in excess may result in negative consequences, thus the intake should be watched. Checking vitamin D levels is advised, and one should speak with a healthcare provider about the right supplements.
- Probiotics
Probiotics are good microorganisms that promote the immune system and gut health. According to some studies, certain probiotic strains could be helpful in immune system regulation and inflammation reduction. Probiotics may be used as supplements or added to fermented meals. However, the precise strains and dosages must be customized to meet individual requirements and should be addressed with a healthcare provider.
- Omega-3 Fatty Acids
Fish oil supplements frequently contain omega-3 fatty acids, which have anti-inflammatory qualities and may lessen the intensity of lupus manifestations. They might help with joint discomfort, inflammation, and heart health. Fish oil supplements must be avoided by people who are on blood thinners or have fish allergies, and their dosages and quality must be carefully evaluated.
Lifestyle Modifications: Changes in lifestyle are essential for controlling lupus symptoms and enhancing general health. Some of these might be eating a balanced diet full of vegetables, fruits, and whole grains, frequent exercise, getting enough rest and sleep, limiting stress, and preventing triggers like prolonged sun exposure.
Natural and Herbal Therapies: As supplemental treatments for lupus, natural and herbal medicines are frequently used. Following are several herbal treatments and natural cures that have been researched for their possible advantages in lupus: –
- Aloe Vera
With its calming and anti-inflammatory qualities, aloe vera gel may help with skin-related complaints like rashes and irritation. To ease discomfort, it may be administered topically to the affected areas. But since some people might be allergic or sensitive to aloe vera, it’s crucial to conduct a small patch test and stop using it if any negative reactions appear.
- Ginger
Due to its anti-inflammatory characteristics, ginger may help reduce lupus-related pain and inflammation. It might be eaten as a supplement or used as a spice in food. Joint pain and problems with digestion may be relieved by ginger tablets or ginger tea.
- Turmeric
An ingredient in turmeric known as curcumin has antioxidant and anti-inflammatory qualities. Curcumin may assist in regulating the immune system and the reduction of inflammation. Although curcumin in larger doses can be found in turmeric, supplementation might be necessary.
- Green Tea
Epigallocatechin gallate (EGCG) is a type of polyphenol found in green tea. EGCG contains anti-inflammatory and antioxidant properties. According to certain studies, green tea can help regulate the body’s immune system and lessen lupus disease activity. Regularly consuming green tea or supplementing it with green tea extract might provide some advantages.
- Evening Primrose Oil
Gamma-linolenic acid (GLA) is an omega-6 fatty acid that belongs to part of evening primrose oil. Due to its anti-inflammatory qualities, GLA may help lessen lupus-related inflammation and symptoms. It is available as a supplement and could be helpful for joint discomfort and skin-related complaints. However, it is essential to discuss the usage involving the oil of evening primrose with a medical expert, especially for people with previous episodes of bleeding or seizure issues.
- Echinacea
The herb echinacea contains immune-stimulating qualities and could support immunological function. Colds and infections are frequently prevented or treated with it. Others might suffer from flare-ups as a result of the immuno-stimulating effects, whereas other lupus sufferers may find it helpful in bolstering their immune systems. So, before consuming echinacea, caution must be used, and it is recommended that you speak with a healthcare provider. Keep in mind that the efficacy and safety regulations for natural herbal treatments differ from those of pharmaceutical medications. To ensure correct supervision, monitoring, and individualized suggestions for the use of herbal treatments and natural cures in the control of lupus, speaking with a medical professional is essential.
Conclusion
The main hallmark of the infamous autoimmune disease, lupus is characterized by the erroneous signaling of the body’s immune system, leading to the assault of its own tissues and organs. There are various types of lupus that impact different parts of the body which range in intensity and severity. Anyone with a specific mutation on the target gene linked to lupus is susceptible to the disease and certain environmental elements such as UV exposure, hormonal changing, lifestyle, infections, etc may worsen lupus symptoms. Due to the complex and intricate disease pathway of lupus, a multidisciplinary approach is commonly used as the standard treatment used for lupus.
Doctors have been prescribing antimalarial drugs, NSAIDs, corticosteroids, biological therapies, and immunosuppressants depending on the symptoms and activity of lupus. There are also alternative treatments aside from prescribed medications which involve natural treatments and lifestyle modifications. These natural treatments bring the most effects when they are personalized and instrumentally combined with the existing prescriptions and correct supervision.
Additional resources for further reference
https://www.aad.org/public/diseases/a-z/lupus-treatment
https://www.webmd.com/lupus/arthritis-lupus
https://my.clevelandclinic.org/health/diseases/4875-lupus
Important Note: The information contained in this article is for general informational purposes only, and should not be construed as health or medical advice, nor is it intended to diagnose, prevent, treat, or cure any disease or health condition. Before embarking on any diet, fitness regimen, or program of nutritional supplementation, it is advisable to consult your healthcare professional in order to determine its safety and probable efficacy in terms of your individual state of health.
Regarding Nutritional Supplements Or Other Non-Prescription Health Products: If any nutritional supplements or other non-prescription health products are mentioned in the foregoing article, any claims or statements made about them have not been evaluated by the U.S. Food and Drug Administration, and such nutritional supplements or other health products are not intended to diagnose, treat, cure, or prevent any disease.
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